2022 Selected Publications
Lili Wang, Nikita Babushkin, Zhonghua Liu, Xuanyao Liu. (2022) Trans-eQTL mapping in gene sets identifies network effects of genetic variants. bioRxiv
Marie Saitou, Andy Dahl, Qingbo Wang, Xuanyao Liu. (2022) Allele frequencies of causal variants have a major impact on low cross-ancestry portability of PRS. bioRxiv
2020 Selected Publications
Xuanyao Liu, Joel A Mefford, Andrew Dahl, Yuan He, Meena Subramaniam, Alexis Battle, Alkes L Price, Noah Zaitlen. (2020) GBAT: a gene-based association test for robust detection of trans-gene regulation. Genome Biology 21 (1), 1-14 Download GBAT package
2019 Selected Publications
Xuanyao Liu, Yang I Li, Jonathan K Pritchard. (2019) Trans effects on gene expression can drive omnigenic inheritance. Cell 177 (4), 1022-1034.
2018 Selected Publications
Xuanyao Liu, Po-Ru Loh, Luke J O’Connor, Steven Gazal, Armin Schoech, Robert M Maier, Nick Patterson, Alkes L Price. (2018) Quantification of genetic components of population differentiation in UK Biobank traits reveals signals of polygenic selection. bioRxiv, 357483
2017 Selected Publications
Xuanyao Liu, Hilary K. Finucane, Alexander Gusev, Gaurav Bhatia, Steven Gazal, Luke O’ Connor, Brendan Bulik-Sullivan, Fred A. Wright, Patrick F. Sullivan, Benjamin M. Neale, Alkes L. Price. (2017) Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues. Americal Journal of Human Genetics 100 (4), 605-616. Download ge-LDSC package
Xuanyao Liu, Dongsheng Lu, Woei-Yuh Saw, et al. (2017) Characterising private and shared signatures of positive selection in 37 Asian populations. European Journal of Human Genetics 25 (4), 499-508
2016 Selected Publications
Xuanyao Liu, Chakravarthi Kanduri, Jaana Oikkonen, Kai Karma, Pirre Raijas, Liisa Ukkola-Vuoti, Yik-Ying Teo, Irma Järvelä. (2016) Detecting signatures of positive selection associated with musical aptitude in the human genome. Scientific Reports 6
2015 Selected Publications
Xuanyao Liu, Yushimah Yunus, Dongsheng Lu, et al., Differential positive selection of malaria resistance genes in three indigenous populations of Peninsular Malaysia. (2015) Human Genetics 134(4), 375-392
2014 Selected Publications
Xuanyao Liu, Woei-Yuh Saw, Mohammad Ali, Rick Twee-Hee Ong, Yik-Ying Teo. (2014) Evaluating the possibility of detecting evidence of positive selection across Asia with sparse genotype data from the HUGO Pan-Asian SNP Consortium. BioMed Central 15(1), 1-14
Xuanyao Liu, Rick Twee-Hee Ong, Esakimuthu Nisha Pillai, Abier M Elzein, Kerrin S Small, Taane G Clark, Dominic P Kwiatkowski, Yik-Ying Teo. (2014) Detecting and characterizing genomic signatures of positive selection in global populations. The American Journal of Human Genetics 92 (6), 866-881. Download haploPS package